
The Inflammation Connection –The New Factor in Heart
Disease, Stroke, Cancer, and other Serious Diseases.
By Marcus Gitterle, MD
One of the early signs of gum disease is that your gums turn from
a pretty pink to an inflamed red. Scientists are now discovering
that bodily inflammation is linked with a host of diseases including
heart disease, stroke, lung disease, cancers, Alzheimer’s,
and others.
Gum disease is an inflammatory condition that does not go away
without treatment and it is a major cause of inflammation in many
people (8) (22). Inflammation causes the liver to secrete a protein
called C-Reactive Protein (CRP, for short) to fight the problem
which seems to cause a number of side effects in the body.
The best known side effect of elevated CRP levels is the connection
to heart disease. CRP is more predictive of heart attacks than the
bad LDL cholesterol (9) (23). While a CRP value of under 1 mg/liter
is considered normal, a value of 2-3 triples your risk of heart
attack and higher values can increase your risk up to seven and
a half times!
(under 1.0 mg/liter). The actual manner by which CRP causes heart
attacks was only recently explained. Elevated CRP levels actually
interfere with the process that prevents blood clots, thus causing
a higher incidence of blockages in arteries which can result in
a sudden heart attack or stroke (10).
By comparison, bad cholesterol slowly builds up plaque in the arteries
which often allows for some advanced warning in the form of pain
or weakness.
While the active process is less known, statistically people with
the top 25% of CRP scores develop 2.5 times as much colon cancer
as those in the bottom 25% (11). Also, CRP is implicated in Alzheimer’s.
Seniors with the highest 1/3 of CRP levels had significantly more
cognitive decline than those in the bottom third (12).
Clearly it pays to know your CRP number, which can be requested
as a single test (a high-sensitivity CRP is the more valuable test
for heart disease association) or when other blood tests are done.
If your CRP is high, the causes need to be determined and corrected
to reduce your number.
In addition to gum disease, bodily infections such as a urinary
tract infection, high blood pressure, smoking, lymphoma, and even
being overweight can contribute to elevated CRP levels. Since periodontal
disease is an inflammatory disease and is capable of elevating CRP
levels, we normally request this blood test for any of our patients
diagnosed with periodontal disease. Centers for Dental Medicine
has developed a groundbreaking protocol for the diagnosis of periodontal
disease and the treatment of periodontal disease and its associated
negative impact on overall health.
Centers throughout the country have found that by following our
unique periodontal protocol, we are able to quickly reduce periodontal
inflammation And in so doing, we can significantly reduce the CRP
level to a non-harmful range in almost all cases, unless there is
another systemic factor contributing to the elevation. (19).
If your CRP number is high to begin with and remains high after
periodontal health has been established, we will collaborate with
your physician to review and monitor your results and make sure
that you do not have other problems as well. As a Center for Dental
Medicine, we give you our exclusive commitment to help care for
your total health.
A Safe, Non-Surgical, Non-Toxic Treatment:
Traditionally, physicians are trained to diagnose disease and treat
with surgery or drugs. The discovery of the infection-inflammation
and heart disease connection is no different.
Physicians are waiting on drug manufacturers to produce a drug
that will lower the levels of CRP and thus, reduce the risk of a
heart attack. An eighteen-month clinical trial showed that a statin
drug (Lipitor) can lower CRP levels (9). However, to accomplish
this, 8 times the normal dosage was needed.
This approach can be expensive and unnecessarily risky. A sole
drug-based approach to lowering CRP levels is not seeking and removing
the underlying cause of the elevated CRP. A more ideal approach
would be to find and eliminate the source of the inflammation in
the first place. A commitment we make to our patients is to help
to eliminate any periodontal inflammation in order to rule out this
potential cause.
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